TransFix is designed to stabilise TBNK surface markers for up to 14 days for flow cytometry analysis. Researchers around the world use TransFix to stabilise over 100 different cellular markers. Cytomark have compiled a list of cellular markers and their …
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Lymph Node Stabilisation
Applications of TransFix: TransFix® Can Be Used to Stabilise Lymph Node Biopsies/Fine Needle Aspirate Specimens for Flow Cytometry Time is critical for the enumeration of cells from lymph node biopsies and other solid tissue via flow cytometry, because cells and …
Read MoreExtracellular Vesicle Isolation from TransFix Stabilised Blood: Preservation of exosome profiles
There has been increasing interest in extracellular vesicles (the “Exosome”) as possible biomarkers for disease and as novel cell-cell communicators. Extracellular vesicles (EVs) carry a variety of cargo such as mRNA, non-coding RNA, proteins and lipids and are thought to …
Read MoreAnimal Blood Stabilisation
TransFix® Has Been Used to Prevent Cellular Degradation in Animal Blood for Analytical Testing Purposes Like with human whole blood specimens, animal whole blood degrades over time rendering it unsuitable for examination. Researchers have found that the addition of TransFix …
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TransFix Stabilisation of Malignant Haematological Cells in Cerebrospinal Fluid
Flow Cytometric Analysis of Cerebrospinal Fluid (CSF) Invasion of leucocytes into cerebrospinal fluid has grave prognostic significance and requires important therapeutic decisions including the administration of intrathecal chemotherapy. Leptomeningeal localisation is conventionally diagnosed by cytomorphological analysis through identification of malignant …
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Bone Marrow Stabilisation
Applications of TransFix: Stabilisation of Bone Marrow for Flow Cytometry Bone marrow (BM) examination is an essential procedure for the evaluation of a variety of clinical haematologic disorders and for preclinical toxicity studies of anti-cancer compounds and immunosuppressive agents. This …
Read MoreBlood Stabilisation: The Importance in a Clinical Setting
Without stabilisation, flow cytometric analysis of blood samples must be performed within 48 hours of venepuncture, as apoptosis and proteolytic degradation of cellular markers will detrimentally affect the immunophenotypic profile. Blood samples older than 48 hours are often no longer …
Read MoreNew Research demonstrates the benefits of TransFix®/EDTA Vacuum Blood Collection Tubes
A new paper published in Cytometry part B, compares two blood stabilising products: the TransFix®/EDTA Vacuum Blood Collection Tube (TVT), and the Streck Cyto-Chex BCT. Key Findings: Comparison of TransFix®/EDTA Vacuum Blood Collection Tube (TVT) and the Streck Cyto-Chex BCT. …
Read MoreImproved Stabilisation, Isolation, and Characterisation of Circulating Tumour Cells
A combination of technologies from French company ScreenCell and British company Cytomark has allowed for improved analysis of single circulating tumour cells. Circulating Tumour Cells The number of circulating tumour cell populations present in patient blood is very low, therefore …
Read MoreInter-laboratory Comparison of the TransFix/EDTA Vacuum Blood Collection Tube (TVT) with the 5 mL Cyto-Chex® BCT
Cytomark, a division of Caltag Medsystems, recently presented a scientific poster at the ICCS2017 conference in collaboration with the Royal Hallamshire Hospital (Sheffield, UK), Royal Sussex County Hospital (Brighton, UK), and Roswell Park Cancer Institute (Buffalo, NY, USA). “Inter-laboratory Comparison of the TransFix/EDTA …
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